Ενημέρωση σχετικά με τα βιβλιογραφικά δεδομένα που αφορούν

 στον Καρκίνο και  COVID-19

Πιο κάτω παρατίθεται απόσπασμα αναφοράς  του ASCO σε θέματα σχετικά με την πανδημία COVID-19 συμπεριλαμβανομένων και σχετικών βιβλιογραφικών αναφορών.

Incidence of COVID-19 among patients with cancer

A report by Yu et al, JAMA Oncol reported on 1524 patients with cancer admitted from December 30, 2019 to February 17, 2020 to an oncology department of a hospital in Wuhan, China.  The authors found that the infection rate among the patients with cancer (0.79% (12 of 1524 patients; 95% CI, 0.3%-1.2%) was higher than the cumulative incidence in the community served by the hospital (0.37%).  Five of the 12 patients were undergoing anti-cancer therapy at the time of hospital admission.

Prevalence of cancer in patients with COVID-19

Desai et al, JCO Glob Oncol identified 11 studies of patients with COVID-19 that reported on the prevalence of cancer in those patients via a systematic review. They found an estimated prevalence of cancer of 2% (95% CI, 2%-3%) in patients treated for COVID-19. Emami et al, Arch Acad Emerg Med reported a similar review and meta-analysis and identified 10 studies and found a prevalence of malignancy of 0.92% (95% CI, 0.56%-1.34%).

However, higher prevalence of cancer in patients with COVID-19 has been seen in studies not included in the systematic reviews due to publication date. Montopoli et al, Ann Oncol reported that among 9,280 patients with COVID-19 treated in 68 hospitals in Veneto, Italy, 8.5% had a diagnosis of cancer.

CANCER-TYPE SPECIFIC GUIDANCE: How should care for patients with cancer types (e.g. breast cancer, lung cancer) be affected?

ASCO does not have guidance specific to management of any cancer type, except as described in the sections below.  However, ASCO will link to such guidance as other organizations publish it.

  • Breast cancer
    • The American Society of Breast Surgeons has published brief, high level guidance on prioritization for care in breast cancer.
    • The American College of Surgeons has published guidance on triage of patients with breast cancer for surgery. 
    • An American multi-organizational panel has published recommendations on the triage, prioritization and treatment of breast cancer (Dietz et al, Breast Cancer Res Treat). An international group has also published recommendations on the same topic (Curigliano et al, Breast)
    • An American group from Johns Hopkins Women’s Malignancies Program has published guidance on care for patients with breast cancer (Sheng et al, JCO Oncol Pract)
  • Gastrointestinal cancers
    • ​An American group of oncologists has developed recommendations for minimizing risks to patients with gastrointestinal malignancies. (Lou et al, JCO Oncol Pract)
    • The US Colorectal Cancer Alliance has published guidance on care for patients with colorectal cancer (Marshall et al, Colorectal Cancer)
    • A French multi-institution group has published guidance on care for patients with peritoneal tumors (Glehen et al, J Visc Surg)
  • Genitourinary cancers
    • Canadian guidance on prioritizing systemic therapy in patients with genitourinary malignancies has been published.  (Lalani et al, Can Urol Assoc J)
    • An editorial in European Urology has presented considerations for the triage of patients for urological surgery, including patients with genitourinary malignancies (Stresland et al, Eur Urol) 
    • Ginsburg et al, J Urol report on analysis of the US National Cancer Database and found no association between delaying radical prostatectomy in patients with prostate cancer by up to 12 months and adverse outcomes.
    • The Canadian Urologic Oncology Group and the Canadian Urological Association have published guidelines for care of patients with prostate cancer (Kokorovic et al, Can Urol Assoc J)
  • Gynecological cancers
    • The editors of the International Journal of Gynecological Cancer have published guidance for management of patients with those cancers. (Ramirez et al, Int J Gynecol Cancer)
    • The National College of French Gynecologists and Obstetricians have published recommendations for the surgical management of gynecological cancers during the COVID-19 pandemic (Akladios et al, J Gynecol Obstet Hum Reprod) 
    • An American multi-institutional group has published recommendations for anti-cancer therapy and surveillance for recurrence of patients with gynecological cancers (Pothuri et al, Gynecol Oncol)
  • Head and neck cancer
    • The French Society of Otorhinolaryngology, Head and Neck Surgery (SFORL) and French Society of Head and Neck Carcinology (SFCCF) have published consensus recommendations on the management of patients requiring head and neck cancer surgery (Fakhry et al, Eur Ann Otorhinolaryngol Head Neck Dis)
    • The MD Anderson Head and Neck Surgery Treatment Guidelines Consortium has published detailed cancer-site specific recommendations for triage for head and neck cancer surgery (Head et al, Head Neck)
  • Hematological malignancy
    • The American Society of Hematology has released guidance related to several different malignancies.
    • The Seattle Cancer Care Alliance has published guidance on managing patients with hematological malignancies (Percival et al, JCO Oncol Pract)
    • Multiple Myeloma
      • An international group of authors has published recommendations on the care of older patients with multiple myeloma (Mian et al, J Geriatr Oncol)
      • A group from the Mayo Clinic has published recommendations regarding management of patients with multiple myeloma (Al Saleh, Acta Haematol)
    • A Brazilian task force has published recommendations on the management of patients with lymphoid malignancies (Perini et al, Hematol Transfus Cell Ther)
    • The French Society for the fight against Cancers and Leukemias in children and adolescents has published guidance on management of young patients with acute lymphoblastic leukemia (Baruchel et al, Bull Cancer)
  • Hepatocellular carcinoma
    • ​The International Liver Cancer Association (ILCA) has released guidance related to are of patients with hepatocellular carcinoma.
  • Lung cancer
    • ​The Thoracic Surgery Outcomes Research Network has published guidance on triage for thoracic surgery for patients with thoracic malignancies (Ann Thorac Surg) 
    • A panel assembled by the journal Chest has published recommendations on management of lung nodules and lung cancer screening (Mazzone et al, Chest)
    • An American group will publish new recommendations on the management of lung cancer in JCO – Oncology Practice in an upcoming issue (Singh et al, JCO Oncol Pract)
  • Neuro-oncology
    • The American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Tumor Section and the Society for Neuro-Oncology (SNO) have published general guidance on care of patients with brain tumors and brain metastases (Ramakrishna et al, J Neurooncol)
    • Guidance specific to management of patients with glioma has been published by an international multi-disciplinary group (Mohile et al, Neuro Oncol)
  • Skin cancer
  • Surgery
    • ​The Society of Surgical Oncology has published brief guidance on surgery for several different disease sites; a summary of this guidance has been published (Bartlett et al, Ann Surg Oncol) 
  • Multiple cancer types

Sourse: American Society of Clinical Oncology – ASCO. COVID-19 Patient Care Information. Last updated 5/18/2020. https://www.asco.org/asco-coronavirus-information/care-individuals-cancer-during-covid-19